The specific formulation of a botulinum toxin dictates how it behaves under the skin. For larger areas like the forehead, many practitioners prefer Dysport, which is famous for its wider “spread,” allowing for a very smooth, natural-looking relaxation of the muscle without feeling heavy. Conversely, for patients who have developed a resistance to traditional toxins over time, Xeomin is a great alternative; it is uniquely formulated as a “naked” or purified neurotoxin, completely free of the accessory proteins that can sometimes trigger an immune response.