Both are used for facial rejuvenation, but they work very differently. Traditional Hyaluronic Acid (HA) fillers provide immediate volume and contouring to specific areas like the lips or cheeks. Biostimulators, on the alternative hand, are injected deep into the dermis to act as a “seed” for your skin. Over several months, they gradually stimulate your body’s own natural collagen production. For long-lasting, global facial structure restoration, Sculptra, a Poly-L-lactic acid biostimulator, is a leading option for treating the underlying causes of facial aging.